EFSA notes there is equivocal evidence of genotoxiciy. | some | European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329. |
EFSA concludes there is limited evidence that Yellow 10 in a mixture with other synthetic colours and sodium benzoate has a "small and statistically significant effect on activity and attention in children selected from the general population". | some | European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329. |
EFSA finds that developmental effects have been observed in animal tests. | some | European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329. |
Very toxic to aquatic life | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Very toxic to aquatic life with long lasting effects | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Suspected of causing genetic defects | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Suspected of causing cancer | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Causes damage to organs through prolonged or repeated exposure | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Very toxic to aquatic life | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Known to cause cancer | some | California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update) |
Suspected of causing genetic defects | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
May cause cancer | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Causes damage to organs through prolonged or repeated exposure | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Very toxic to aquatic life | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Very toxic to aquatic life with long lasting effects | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Fatal if inhaled Only in: Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Suspected of damaging fertility. | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Suspected of damaging the unborn child. | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Carcinogenic to humans | some | International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127) |
Known To Be Human Carcinogen | some | National Toxicology Program (NTP): NTP 14th Report on Carcinogens |
Probably carcinogenic to humans | some | Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer |
Probably carcinogenic to humans | some | International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127) |
Probably carcinogenic to humans | some | Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer |
A review article reports equivocal evidence of genotoxicity, including in human cell assays. | some | Peer Reviewed Literature: Amchova, P., H. Kotolova & J. Ruda-Kucerova. 2015. Health safety issues of synthetic food colorants. Regulatory toxicology and pharmacology : RTP 73(3), 914-22. |
A review article reports equivocal evidence of genotoxicity, including in human cell assays. | some | Peer Reviewed Literature: Amchova, P., H. Kotolova & J. Ruda-Kucerova. 2015. Health safety issues of synthetic food colorants. Regulatory toxicology and pharmacology : RTP 73(3), 914-22. |
Toxic if swallowed Only in: Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Toxic in contact with skin Only in: Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Toxic if inhaled Only in: Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
kidney damage | some | American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis |
suspected human carcinogen | some | American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis |
A peer-reviewed study reports endocrine activity in cellular assays. | some | Patrick Tarnow, Catrin Zordick, Alex Bottke, Berit Fischer, Friederike Kühne, Tewes Tralau & Andreas Luch. 2020. Characterization of Quinoline Yellow Dyes As Transient Aryl Hydrocarbon Receptor Agonists. Chemical research in toxicology 33(3), 742-750. |
Suspected of damaging fertility or the unborn child Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
suspected of causing genetics defects Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
causes damage to organs through prolonged or repeated exposure Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
EFSA notes that Yellow 10 intolerance/sensitivity have been reported. | some | European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re‐evaluation of Quinoline Yellow (E 104) as a food additive. EFSA Journal 7(11), 1329. |
confirmed animal carcinogen with unknown relevance to humans | some | American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis |
May cause an allergic skin reaction Only in: Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
NTP Toxcast scored 1.5-2.5 | some | National Toxicology Program (NTP): EWG Toxcast Analysis |
NTP Toxcast scored 1.5-2.5 | some | National Toxicology Program (NTP): EWG Toxcast Analysis |
Toxic in contact with skin Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
toxic if inhaled Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
Toxic of swallowed Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
SCCS notes there is limited evidence of skin irritation. | some | European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3. |
Causes serious eye damage Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners | some | EU GHS Hazard Labeling Codes: GHS Hazard Codes |
Harmful if swallowed Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
harmful in inhaled Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
may cause damage to organs through prolonged or repeated exposure Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
May cause an allergic skin reaction Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
may cause respiratory irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
May cause an allergic skin reaction Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
may cause respiratory irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
Causes serious eye damage Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
Causes skin irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
Causes skin irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
Causes serious eye damage Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
causes serious eye irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
causes serious eye irritation Only in: Household Cleaners | some | European Chemicals Agency (ECHA): GHS Data from ECHA Website |
SCCS notes there is limited evidence of eye irritation. | low | European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3. |
Not classifiable as to human carcinogenicity | low | Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer |
Not known to cause asthma | low | Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update) |
Not classifiable as to its carcinogenicity to humans | low | International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127) |
EPA testing shows this substance has moderate acute toxicity to aquatic life | low | Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database |
No evidence of skin sensitization in limited human and animal tests. | low | European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3. |
EPA testing shows this substance has low acute toxicity to aquatic life | low | Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database |
Low acute oral toxicity in animal studies. | low | European Commission, Scientific Committee on Consumer Safety (SCCS). 2004. OPINION OF THE SCIENTIFIC COMMITTEE ON COSMETIC PRODUCTS AND NON-FOOD PRODUCTS INTENDED FOR CONSUMERS Concerning Acid Yellow 3. |
FAQs
D&C Yellow No. 10 (CI 47005) | Substance? ›
D&C Yellow 10 is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics.
What is D&C yellow number 10? ›10 Powder is a water-soluble powdered dye also known as Acid Yellow 3. D&C Yellow No. 10 Powder is used in drug and cosmetic applications and environments. May be used for coloring contact lenses in amounts not to exceed the minimum reasonable required to accomplish the intended color.
What is CI 47005 in skin care? ›CI 47005 is considered safe for use in cosmetics by the USFDA however, it is known to be irritating to the skin and eyes, and may be an endocrine disruptor affecting the hormone production in the body.
Is CL 47005 safe? ›10 (Ci 47005) Lake. Products with this ingredient are allowed for use in EWG VERIFIED but must meet use restrictions and warnings based on EWG review of company data.
What is D&C yellow? ›D&C Yellow # 10 (2-(2-Quinolyl)-1,3-indandione disulfonic acid disodium salt) is a FDA-approved colorant commonly used to color dose forms such as tablets and capsules. FD&C colors are the colors certified for use by the U.S. FDA in the food, drug, and cosmetic industry.
Is yellow 10 safe? ›D&C Yellow 10 is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics.
What does D&C mean in color? ›FDA-Approved Dyes and Lakes for Cosmetic Applications
FD&C (Food, Drugs and Cosmetics) and D&C (Drugs & Cosmetics) dyes and lakes, also known as artificial colors or certified colors, can be used in a wide range of combinations to produce nearly any color imaginable for cosmetic products.
Quinoline yellow, which is banned in food in the USA, Australia, and Norway, can trigger contact allergic reactions (contact eczema). In addition, it had a nerve- and mutagenic effect in test tube experiments.
Is quinoline yellow harmful? ›The material is not thought to produce adverse health effects following ingestion (as classified using animal models).
What are the side effects of Yellow 5? ›Tartrazine, also known as Yellow 5, has been associated with behavioral changes including irritability, restlessness, depression and difficulty with sleeping ( 10 ). What's more, a 2004 analysis of 15 studies concluded that artificial food dyes do increase hyperactivity in children ( 11 ).
What is yellow 10 made of? ›
D&C Yellow No. 10 is manufactured by condensing quinaldine with phthalic anhydride to give the unsulfonated dye, which is then sulfonated with oleum.
Why would you get a D&C? ›A D&C procedure may be done for different reasons, including to look for the cause of a problem, such as abnormal uterine bleeding; for treatment of a miscarriage or postpregnancy bleeding; or for first trimester abortion (pregnancy termination).
What is D&C colours? ›Known as drug & cosmetic colours suitable for tablet coatings, compressed tablets, syrups, hard & soft gelatin capsules, toiletries, skin-care products, water-based make-up, lipstick, nail polish, pencil, foundation and lip gloss.
What is a yellow pain pill with 10 on it? ›Generally, yellow Percocet is the 10mg/325mg prescription, regardless of whether it's generic or brand name. Lower doses of Percocet tend to be white and round. It may be imprinted with “Percocet” if it's the brand name, and it may also have a number on it that represents how much oxycodone it contains.
What is D&C Colours? ›Known as drug & cosmetic colours suitable for tablet coatings, compressed tablets, syrups, hard & soft gelatin capsules, toiletries, skin-care products, water-based make-up, lipstick, nail polish, pencil, foundation and lip gloss.
What is a yellow pill with S 10 on it? ›JARDIANCE tablets available as: 10 mg pale yellow, round, biconvex and bevel-edged, film-coated tablets debossed with "S 10" on one side and the Boehringer Ingelheim company symbol on the other side.
What is a yellow pill with T 10 on it? ›Tadalafil is used in the treatment of Benign Prostatic Hyperplasia; Erectile Dysfunction; Pulmonary Arterial Hypertension and belongs to the drug classes agents for pulmonary hypertension, impotence agents.